Summary
Leading scientists, including Nobel laureates, are urging a halt to research on creating “mirror life” microbes, citing “unprecedented risks” to life on Earth.
Mirror microbes, built from reversed molecular structures, could evade natural immune systems, leading to uncontrollable lethal infections.
While mirror molecules hold potential for medical and industrial uses, researchers warn that mirror organisms could escape containment and resist antibiotics.
A 299-page report in Science advocates banning such research until safety can be ensured and calls for global debate on its ethical and ecological implications.
It’s worth bearing in mind that opposite chirality is not inherently dangerous. Whether an individual mirror molecule poses a problem depends on the specific biochemical context. While there have been famous situations where a chiral enantiomer proved toxic, for every one of these there’s been plenty more instances where biology shrugs and doesn’t gaf.
Does this mean we shouldn’t worry? Obviously not, but it just means we should do more to manage the general risks of molecular engineering for microbes. Chirality is only one of many, many routes through which risks can come, so there’s no point fixating on that.