I never thought about it before but I use upstream and downstream without much though. For my personal devices and containers I use Fedora but when it comes to servers and VMs I use Debian for its stable nature.
I also run Linux mint in my homelab with pcie pass though so it functions like a normal desktop.
Those are both good distros for those purposes. I’m not a fan of Debian as a desktop distro but it’s awesome as a headless server, and Fedora moves too fast for my tastes as a server distro but that’s fine in a desktop.
So good choice.