I’ll go first: “You have to have children when you’re young,” told to me when I was in my late 20s, with no desire to ever have kids, and no means to support them, by someone divorced multiple times with at least one adult child who does not speak to them.
Also: Responding to “How do I deal with this problem?” questions with “Oh, don’t worry about it, it’s enough that you’re even thinking about it!”
This is the big one for me. My co-workers all wonder why I switched from pc to PlayStation, and I’m like, “dude, you just watched me troubleshoot 10 machines that failed our OS upgrade, and you think I want to come home and find that Windows update just broke my sound drivers again?”